Randomized, Phase III Study of Early Intervention With Venetoclax and Obinutuzumab Versus Delayed Therapy With Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study EVOLVE
Verified

What's the purpose of this trial?

In this study, researchers are comparing early treatment with venetoclax and obinutuzumab versus delayed treatment with these two medications in patients with newly diagnosed high-risk chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who are not experiencing symptoms. Starting treatment with these drugs early (before patients have symptoms) may be more effective than delaying treatment until symptoms emerge.

Venetoclax may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Obinutuzumab may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Venetoclax is taken orally (by mouth) and obinutuzumab is given intravenously (by vein). Patients will be randomly assigned to receive treatment either before or after they have symptoms.

This trial is currently open and accepting patients.

You may be able to join this trial if you:

The following criteria is a partial list of reasons why patients may be eligible to participate in this clinical trial. Further evaluation with a medical professional is required.

To be eligible for this study, patients must meet several criteria, including but not limited to the following:

  • Patients must have previously untreated high-risk CLL or SLL that is not yet causing symptoms.
  • Patients must be able to walk and do routine activities for more than half of their normal waking hours.
  • This study is for patients age 18 and older.

Additional Trial Information

Phase 3

Enrollment: 247 patients (estimated)

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Need Help?

Interested in joining or learning more about this trial?

(888) 828-2206

Trial Locations

All Trial Locations

View all clinical trial locations sorted by state.

Alaska

Anchorage Associates in Radiation Medicine

Anchorage, AK

Temporarily Suspended

Anchorage Radiation Therapy Center

Anchorage, AK

Temporarily Suspended

Alaska Breast Care and Surgery LLC

Anchorage, AK

Temporarily Suspended

Alaska Oncology and Hematology LLC

Anchorage, AK

Temporarily Suspended

Alaska Women's Cancer Care

Anchorage, AK

Temporarily Suspended

Anchorage Oncology Centre

Anchorage, AK

Temporarily Suspended

Katmai Oncology Group

Anchorage, AK

Temporarily Suspended

Providence Alaska Medical Center

Anchorage, AK

Temporarily Suspended

Fairbanks Memorial Hospital

Fairbanks, AK

Open and Accepting

Arizona

Banner Health University Medical Center

Tucson, AZ

Open and Accepting

University of Arizona Cancer Center

Tucson, AZ

Open and Accepting

Arkansas

Mercy Hospital Fort Smith

Fort Smith, AR

Temporarily Suspended

CHI St. Vincent Hot Springs Cancer Center

Hot Springs, AR

Temporarily Suspended

California

Kaiser Permanente Orange County - Anaheim Medical Center

Anaheim, CA

Open and Accepting

Kaiser Permanente Baldwin Park Medical Center

Baldwin Park, CA

Open and Accepting

Kaiser Permanente (Bellflower Medical Offices)

Bellflower, CA

Open and Accepting

Roy and Patricia Disney Family Cancer Center Providence Saint Joseph Medical Center

Burbank, CA

Temporarily Suspended

Marshall Cancer Center

Cameron Park, CA

Open and Accepting

UCI Health - Costa Mesa

Costa Mesa, CA

Open and Accepting

City of Hope Comprehensive Cancer Center Beckman Research Institute

Duarte, CA

Open and Accepting

Kaiser Permanente (Fontana Medical Center)

Fontana, CA

Open and Accepting

Kaiser Permanente Orange County Irvine Medical Center

Irvine, CA

Open and Accepting

City of Hope Orange County Lennar Foundation Cancer Center

Irvine, CA

Open and Accepting

UCI Health (Laguna Hills)

Laguna Hills, CA

Open and Accepting

Rideout Cancer Center (Fremont)

Linda, CA

Open and Accepting

Kaiser Permanente (South Bay Medical Center)

Los Angeles, CA

Open and Accepting

Kaiser Permanente Los Angeles Medical Center

Los Angeles, CA

Open and Accepting

Kaiser Permanente (Panorama City Medical Center)

Los Angeles, CA

Open and Accepting

Kaiser Permanente (Woodland Hills Medical Center)

Los Angeles, CA

Open and Accepting

Kaiser Permanente (West Los Angeles)

Los Angeles, CA

Open and Accepting

Chao Family Comprehensive Cancer Center University of California, Irvine

Orange, CA

Open and Accepting

Kaiser Permanente (Riverside Medical Center)

Riverside, CA

Open and Accepting

University of California Davis Comprehensive Cancer Center

Sacramento, CA

Open and Accepting

Kaiser Permanente (San Diego Medical Center)

San Diego, CA

Open and Accepting

Kaiser Permanente (San Marcos Medical Offices)

San Marcos, CA

Open and Accepting

Colorado

Rocky Mountain Cancer Centers

Aurora, CO

Open and Accepting

The Medical Center of Aurora (HealthONE)

Aurora, CO

Temporarily Suspended

Rocky Mountain Cancer Center Boulder

Boulder, CO

Temporarily Suspended

Rocky Mountain Cancer Centers - Centennial

Centennial, CO

Temporarily Suspended

Littleton Adventist Hospital

Centennial, CO

Temporarily Suspended

The Women's Imaging Center

Denver, CO

Temporarily Suspended

Porter Adventist Hospital

Denver, CO

Temporarily Suspended

Colorado Blood Cancer Institute Sarah Cannon at Presbyterian/St. Luke's Medical Center (HealthONE)

Denver, CO

Temporarily Suspended

Rocky Mountain Cancer Centers (Midtown)

Denver, CO

Open and Accepting

SCL Health Saint Joseph Hospital

Denver, CO

Temporarily Suspended

Rocky Mountain Cancer Centers (Rose Medical) Denver

Denver, CO

Open and Accepting

HealthOne Rose Medical Center

Denver, CO

Temporarily Suspended

Western Surgical Care

Denver, CO

Temporarily Suspended

Centura Southwest Oncology

Durango, CO

Temporarily Suspended

The Melanoma and Skin Cancer Institute

Englewood, CO

Temporarily Suspended

Rocky Mountain Cancer Centers - Englewood Swedish Medical Center

Englewood, CO

Open and Accepting

Mountain Blue Cancer Care Center

Englewood, CO

Temporarily Suspended

SCL Health St. Mary's Medical Center

Grand Junction, CO

Temporarily Suspended

SCL Health Good Samaritan Medical Center

Lafayette, CO

Temporarily Suspended

Rocky Mountain Cancer Centers - Lakewood

Lakewood, CO

Temporarily Suspended

Rocky Mountain Cancer Center Littleton

Littleton, CO

Open and Accepting

Rocky Mountain Cancer Centers - Sky Ridge Medical Center (Lone Tree) Lone Tree - Skyridge

Lone Tree, CO

Open and Accepting

HealthOne Sky Ridge Medical Center

Lone Tree, CO

Temporarily Suspended

Rocky Mountain Cancer Centers (Longmont) Longmont

Longmont, CO

Temporarily Suspended

Centura Parker Adventist Hospital

Parker, CO

Temporarily Suspended

Rocky Mountain Cancer Center - Thornton

Thornton, CO

Temporarily Suspended

Delaware

Beebe South Coastal Health Campus

Frankford, DE

Open and Accepting

Beebe Medical Center

Lewes, DE

Temporarily Suspended

Medical Oncology Hematology Consultants PA in ChristianaCare Helen F. Graham Cancer Center & Research Institute

Newark, DE

Open and Accepting

Christiana Care Health System (Christiana Hospital)

Newark, DE

Temporarily Suspended

Beebe Health Campus

Rehoboth Beach, DE

Open and Accepting

Nanticoke Memorial Hospital

Seaford, DE

Temporarily Suspended

Christiana Care Health System (Wilmington Hospital)

Wilmington, DE

Temporarily Suspended

Florida

Holy Cross Hospital

Fort Lauderdale, FL

Open and Accepting

Idaho

Saint Alphonsus Cancer Care Center (Boise)

Boise City, ID

Open and Accepting

Saint Alphonsus Cancer Care Center (Caldwell)

Caldwell, ID

Open and Accepting

Kootenai Clinic Cancer Services - Coeur d'Alene

Coeur d'Alene, ID

Open and Accepting

Walter Knox Memorial Hospital

Emmett, ID

Temporarily Suspended

Saint Luke's Mountain States Tumor Institute (Fruitland)

Fruitland, ID

Temporarily Suspended

Idaho Urologic Institute

Meridian, ID

Temporarily Suspended

St. Luke's Cancer Institute (Meridian)

Meridian, ID

Temporarily Suspended

Saint Luke's Mountain States Tumor Institute (Nampa)

Nampa, ID

Temporarily Suspended

Saint Alphonsus Cancer Care Center (Nampa)

Nampa, ID

Open and Accepting

Kootenai Cancer Center

Post Falls, ID

Open and Accepting

Kootenai Clinic

Sandpoint, ID

Open and Accepting

Saint Luke's Mountain States Tumor Institute (Twin Falls)

Twin Falls, ID

Temporarily Suspended

Illinois

OSF Saint Anthony's Health

Alton, IL

Temporarily Suspended

Rush - Copley Medical Center

Aurora, IL

Temporarily Suspended

Loyola Center for Health at Burr Ridge

Burr Ridge, IL

Temporarily Suspended

Memorial Hospital of Carbondale

Carbondale, IL

Temporarily Suspended

SIH Cancer Institute

Carterville, IL

Temporarily Suspended

Centralia Oncology Clinic

Centralia, IL

Temporarily Suspended

University of Chicago Medicine Comprehensive Cancer Center

Chicago, IL

Open and Accepting

Robert H. Lurie Comprehensive Cancer Center Northwestern University Feinberg School of Medicine

Chicago, IL

Open and Accepting

Carle Foundation Hospital (Vermilion)

Danville, IL

Open and Accepting

Cancer Care Specialists of IL - Cancer Care Center of Decatur

Decatur, IL

Open and Accepting

Memorial Health - Decatur Memorial Hospital Memorial Health

Decatur, IL

Temporarily Suspended

Northwestern Medicine Cancer Center (Kishwaukee)

DeKalb, IL

Open and Accepting

Carle (Effingham)

Effingham, IL

Open and Accepting

Cancer Care Specialists (Crossroads Cancer Center)

Effingham, IL

Open and Accepting

Elmhurst Memorial Hospital

Elmhurst, IL

Open and Accepting

NorthShore University Health System - Evanston Hospital

Evanston, IL

Open and Accepting

Western Illinois Cancer Treatment Center

Galesburg, IL

Temporarily Suspended

Northwestern Medicine Cancer Center Delnor

Geneva, IL

Open and Accepting

NorthShore University Health System Glenbrook Hospital

Glenview, IL

Open and Accepting

Northwestern Medicine Grayslake Outpatient Center

Grayslake, IL

Open and Accepting

NorthShore University Health System (Highland Park Hospital)

Highland Park, IL

Open and Accepting

Loyola Medicine Homer Glen

Homer Glen, IL

Temporarily Suspended

Northwestern Medicine Lake Forest Hospital

Lake Forest, IL

Open and Accepting

Carle Foundation Hospital (Mattoon)

Mattoon, IL

Open and Accepting

Loyola University Medical Center Cardinal Bernardin Cancer Center

Maywood, IL

Open and Accepting

Marjorie Weinberg Cancer Center at Loyola-Gottlieb

Melrose Park, IL

Temporarily Suspended

Good Samaritan Regional Health Center

Mount Vernon, IL

Temporarily Suspended

University of Chicago Cancer Center at Silver Cross

New Lenox, IL

Open and Accepting

Cancer Care Center of O'Fallon

O'Fallon, IL

Open and Accepting

University of Chicago Medicine Orland Park

Orland Park, IL

Open and Accepting

Methodist Medical Center of Illinois

Peoria, IL

Temporarily Suspended

Southern Illinois University School of Medicine - Simmons Cancer Institute

Springfield, IL

Open and Accepting

Springfield Clinic Main Campus East

Springfield, IL

Open and Accepting

Memorial Medical Center

Springfield, IL

Temporarily Suspended

Carle Cancer Institute

Urbana, IL

Open and Accepting

Northwestern Medicine Cancer Center Warrenville

Warrenville, IL

Open and Accepting

Rush - Copley Healthcare Center

Yorkville, IL

Temporarily Suspended

Indiana

Simon Cancer Center Indiana University

Indianapolis, IN

Open and Accepting

Iowa

Mary Greeley Medical Center

Ames, IA

Open and Accepting

McFarland Clinic PC

Ames, IA

Open and Accepting

Mission Cancer & Blood

Ankeny, IA

Open and Accepting

McFarland Clinic PC (Boone)

Boone, IA

Open and Accepting

Saint Anthony Regional Hospital

Carroll, IA

Temporarily Suspended

Iowa Blood and Cancer Care of PCI

Cedar Rapids, IA

Open and Accepting

MercyOne Clive Cancer Center

Clive, IA

Temporarily Suspended

Mission Cancer & Blood (Clive) In Clive Cancer Center

Clive, IA

Open and Accepting

Greater Regional Medical Center

Creston, IA

Temporarily Suspended

Mission Cancer and Blood - Des Moines

Des Moines, IA

Open and Accepting

Broadlawns Medical Center

Des Moines, IA

Open and Accepting

MercyOne Des Moines Medical Center

Des Moines, IA

Open and Accepting

Mission Cancer MercyOne Cancer Center (Laurel)

Des Moines, IA

Open and Accepting

Iowa Lutheran Hospital

Des Moines, IA

Temporarily Suspended

UnityPoint Health - Iowa Methodist Medical Center

Des Moines, IA

Open and Accepting

McFarland Clinic Trinity Cancer Center

Fort Dodge, IA

Open and Accepting

McFarland Clinic PC (Jefferson)

Jefferson, IA

Open and Accepting

McFarland Clinic PC (Marshalltown)

Marshalltown, IA

Open and Accepting

Mission Cancer and Blood

Waukee, IA

Open and Accepting

MercyOne West Des Moines Medical Center

West Des Moines, IA

Temporarily Suspended

UnityPoint Health - Methodist West Hospital

West Des Moines, IA

Temporarily Suspended

Kansas

Central Care Cancer Center (Heartland)

Garden City, KS

Temporarily Suspended

Central Care Cancer Center - Great Bend

Great Bend, KS

Temporarily Suspended

Hays Medical Center

Hays, KS

Open and Accepting

University of Kansas Cancer Center

Kansas City, KS

Open and Accepting

Lawrence Memorial Hospital

Lawrence, KS

Open and Accepting

Olathe Medical Center

Olathe, KS

Open and Accepting

University of Kansas Cancer Center (Overland Park)

Overland Park, KS

Open and Accepting

Salina Regional Health Center

Salina, KS

Temporarily Suspended

University of Kansas Health System St. Francis Campus

Topeka, KS

Open and Accepting

University of Kansas Cancer Center (Westwood)

Westwood, KS

Open and Accepting

Kentucky

Saints Mary and Elizabeth Hospital

Louisville, KY

Temporarily Suspended

Jewish Hospital Medical Center Northeast

Louisville, KY

Temporarily Suspended

Jewish Hospital Medical Center South

Shepherdsville, KY

Temporarily Suspended

Maine

Harold Alfond Center for Cancer Care MaineGeneral Medical Center

Augusta, ME

Open and Accepting

SMHC Cancer Care - Brunswick MaineHealth

Brunswick, ME

Open and Accepting

Maine Medical Center - Bramhall Campus MaineHealth

Portland, ME

Open and Accepting

MaineHealth Cancer Care - South Portland

South Portland, ME

Open and Accepting

Maryland

Sidney Kimmel Comprehensive Cancer Center Johns Hopkins Medicine

Baltimore, MD

Open and Accepting

Walter Reed National Military Medical Center

Bethesda, MD

Open and Accepting

Holy Cross Hospital

Wheaton, MD

Open and Accepting

Massachusetts

Tufts Medical Center Cancer Center

Boston, MA

Open and Accepting

Dana-Farber Cancer Institute

Boston, MA

Open and Accepting

Michigan

ProMedica Hickman Cancer Center Grace Christman Medical Building

Adrian, MI

Temporarily Suspended

Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, MI

Open and Accepting

Bronson Battle Creek Cancer Care Center

Battle Creek, MI

Open and Accepting

IHA Hematology Oncology at St. Joe's Brighton

Brighton, MI

Open and Accepting

St. Joseph Mercy Brighton Health Center

Brighton, MI

Open and Accepting

Henry Ford Institute - Brownstown

Brownstown Charter Township, MI

Temporarily Suspended

Michigan Cancer Research Consortium - Trinity Health Medical Center – Canton

Canton, MI

Open and Accepting

St. Joseph Mercy Canton Health Center

Canton, MI

Open and Accepting

Caro Cancer Center

Caro, MI

Temporarily Suspended

Chelsea Hospital Michigan Cancer Research Consortium

Chelsea, MI

Open and Accepting

IHA Hematology Oncology at St. Joe's Chelsea

Chelsea, MI

Open and Accepting

Hematology Oncology Consultants (Clarkston)

Clarkston, MI

Open and Accepting

Newland Medical Associates of Clarkston

Clarkston, MI

Open and Accepting

Henry Ford Macomb Hospital

Clinton Township, MI

Open and Accepting

Henry Ford Medical Center (Fairlane)

Dearborn, MI

Temporarily Suspended

Henry Ford Hospital

Detroit, MI

Open and Accepting

Great Lakes Cancer Management Specialists (Doctors Park)

East China, MI

Open and Accepting

Genesys Hurley Cancer Institute

Flint, MI

Open and Accepting

Hurley Medical Center

Flint, MI

Open and Accepting

The Cancer & Hematology Centers

Flint, MI

Temporarily Suspended

Corewell Health Lemmen-Holton Cancer Pavilion Corewell Health Butterworth

Grand Rapids, MI

Open and Accepting

Trinity Health Grand Rapids Hospital

Grand Rapids, MI

Open and Accepting

Helen DeVos Children's Hospital

Grand Rapids, MI

Temporarily Suspended

Academic Hematology Oncology Specialists Ascension St. John Hospital

Grosse Pointe Woods, MI

Open and Accepting

Great Lakes Cancer Management Specialists (Van Elslander Cancer Center) Ascension St. John Hospital

Grosse Pointe Woods, MI

Open and Accepting

Ascension Medical Group Michigan Breast Specialists

Grosse Pointe Woods, MI

Temporarily Suspended

Allegiance Health

Jackson, MI

Open and Accepting

Bronson Methodist Hospital

Kalamazoo, MI

Open and Accepting

West Michigan Cancer Center

Kalamazoo, MI

Open and Accepting

Cancer Research Consortium of West Michigan - Ascension Borgess Cancer Medical Center

Kalamazoo, MI

Open and Accepting

Borgess Medical Center

Kalamazoo, MI

Temporarily Suspended

McLaren Greater Lansing - Mid-Michigan Physicians

Lansing, MI

Open and Accepting

St. Mary Mercy Hospital St. Joe's Health

Livonia, MI

Open and Accepting

Great Lakes Cancer Management Specialists (Macomb Medical Campus)

Macomb, MI

Open and Accepting

Michigan Breast Specialists-Macomb Township

Macomb, MI

Temporarily Suspended

Michigan Cancer Research Consortium - Saint Mary's Oncology/Hematology Associates of Marlette

Marlette, MI

Temporarily Suspended

Toledo Clinic Cancer Centers (Monroe)

Monroe, MI

Temporarily Suspended

Trinity Health Muskegon Hospital

Muskegon, MI

Open and Accepting

Lakeland Community Hospital

Niles, MI

Open and Accepting

Cancer & Hematology Centers of Western Michigan - Muskegon

Norton Shores, MI

Open and Accepting

Henry Ford Medical Center (Columbus)

Novi, MI

Open and Accepting

Newland Medical Associates (Pontiac) The Alice Gustafson Center

Pontiac, MI

Open and Accepting

St. Joseph Mercy (Oakland)

Pontiac, MI

Open and Accepting

Spectrum Health Reed City Hospital

Reed City, MI

Open and Accepting

Ascension St. Mary's Hospital

Saginaw, MI

Open and Accepting

Oncology Hematology Associates of Saginaw Valley PC

Saginaw, MI

Temporarily Suspended

Henry Ford Macomb Health Center (Shelby Township)

Shelby, MI

Temporarily Suspended

Ascension Providence Cancer Center (Foster Winter Drive)

Southfield, MI

Open and Accepting

Spectrum Health Lakeland Medical Center

St. Joseph, MI

Temporarily Suspended

Spectrum Health Marie Yeager Cancer Center

St. Joseph, MI

Open and Accepting

Bhadresh Nayak MD PC - Sterling Heights

Sterling Heights, MI

Temporarily Suspended

Ascension Saint Joseph Hospital

Tawas City, MI

Temporarily Suspended

Munson Medical Center

Traverse City, MI

Open and Accepting

Michigan Cancer Research Consortium - Advanced Breast Care Center PLLC

Warren, MI

Temporarily Suspended

Michigan Breast Specialists-Warren

Warren, MI

Temporarily Suspended

Henry Ford Medical Center (West Bloomfield)

West Bloomfield, MI

Open and Accepting

University of Michigan Health - West

Wyoming, MI

Open and Accepting

Huron Gastroenterology PC

Ypsilanti, MI

Open and Accepting

Minnesota

M Health Fairview Ridges Hospital

Burnsville, MN

Temporarily Suspended

Minnesota Oncology - Burnsville

Burnsville, MN

Temporarily Suspended

Cambridge Medical Center

Cambridge, MN

Temporarily Suspended

Mercy Hospital

Coon Rapids, MN

Open and Accepting

Essentia Health

Deer River, MN

Open and Accepting

Essentia Health (Duluth Clinic)

Duluth, MN

Open and Accepting

Fairview Southdale Hospital

Edina, MN

Temporarily Suspended

Essentia Health Hibbing Clinic

Hibbing, MN

Open and Accepting

Fairview Maple Grove Medical Center

Maple Grove, MN

Temporarily Suspended

Minnesota Oncology Maplewood Cancer Center

Maplewood, MN

Temporarily Suspended

Abbott-Northwestern Hospital Allina Health Cancer Institute

Minneapolis, MN

Temporarily Suspended

Hennepin County Medical Center

Minneapolis, MN

Temporarily Suspended

Minneapolis VA Medical Center

Minneapolis, MN

Open and Accepting

Health Partners Inc.

Minneapolis, MN

Temporarily Suspended

Monticello Cancer Center

Monticello, MN

Temporarily Suspended

New Ulm Medical Center

New Ulm, MN

Temporarily Suspended

Fairview Northland Medical Center

Princeton, MN

Temporarily Suspended

North Memorial Medical Health Center

Robbinsdale, MN

Temporarily Suspended

Essentia Health (Sandstone)

Sandstone, MN

Open and Accepting

Saint Francis Regional Medical Center

Shakopee, MN

Open and Accepting

Coborn Cancer Center at Saint Cloud Hospital

St. Cloud, MN

Open and Accepting

Park Nicollet Clinic

St. Louis Park, MN

Open and Accepting

Regions Hospital

St. Paul, MN

Temporarily Suspended

United Hospital

St. Paul, MN

Temporarily Suspended

Lakeview Hospital

Stillwater, MN

Temporarily Suspended

Essentia Health Virginia Clinic

Virginia, MN

Open and Accepting

Ridgeview Medical Center

Waconia, MN

Open and Accepting

Rice Memorial Hospital

Willmar, MN

Temporarily Suspended

Minnesota Oncology and Hematology PA (Woodbury)

Woodbury, MN

Temporarily Suspended

Fairview Lakes Medical Center

Wyoming, MN

Temporarily Suspended

Mississippi

Baptist Memorial Hospital and Cancer Center-Golden Triangle

Columbus, MS

Open and Accepting

Baptist Cancer Center-Grenada

Grenada, MS

Open and Accepting

Baptist Memorial Hospital and Cancer Center-Union County

New Albany, MS

Open and Accepting

Baptist Memorial Hospital and Cancer Center-Desoto

Southhaven, MS

Open and Accepting

Missouri

Saint Louis Cancer and Breast Institute

Ballwin, MO

Temporarily Suspended

Central Care Cancer Center

Bolivar, MO

Temporarily Suspended

Saint Francis Medical Center (Cape Girardeau)

Cape Girardeau, MO

Open and Accepting

Southeast Cancer Center Southeast Health

Cape Girardeau, MO

Temporarily Suspended

St. Luke's Hospital

Chesterfield, MO

Open and Accepting

Parkland Health Center (Farmington)

Farmington, MO

Open and Accepting

Capital Region Medical Center (Goldschmidt Cancer Center)

Jefferson City, MO

Temporarily Suspended

Freeman Cornell-Beshore Cancer Institute

Joplin, MO

Temporarily Suspended

Mercy Hospital Joplin

Joplin, MO

Temporarily Suspended

Kansas City Cancer Centers (North)

Kansas City, MO

Open and Accepting

Truman Medical Center

Kansas City, MO

Open and Accepting

Kansas City Cancer Center (Lee's Summit)

Lees Summit, MO

Open and Accepting

Mercy Clinic Cancer and Hematology (Rolla)

Rolla, MO

Temporarily Suspended

Phelps Health Hospital Delbert Day Cancer Institute

Rolla, MO

Open and Accepting

Sainte Genevieve County Memorial Hospital

Sainte Genevieve, MO

Open and Accepting

Mercy Hospital Springfield

Springfield, MO

Temporarily Suspended

CoxHealth South Hospital Cox Medical Center South

Springfield, MO

Temporarily Suspended

Heartland Regional Medical Center

St. Joseph, MO

Temporarily Suspended

Saint Louis Cancer and Breast Institute (South City)

St. Louis, MO

Temporarily Suspended

Mercy Hospital South

St. Louis, MO

Open and Accepting

Missouri Baptist Medical Cancer Center

St. Louis, MO

Open and Accepting

Mercy Hospital St. Louis David C. Pratt Cancer Center

St. Louis, MO

Open and Accepting

Missouri Baptist Sullivan Hospital

Sullivan, MO

Open and Accepting

Missouri Baptist Outpatient Center (Sunset Hills)

Sunset Hills, MO

Open and Accepting

Mercy Hospital Washington

Washington, MO

Temporarily Suspended

Montana

Community Hospital of Anaconda

Anaconda, MT

Open and Accepting

Billings Clinic Cancer Center

Billings, MT

Open and Accepting

St. Vincent Frontier Cancer Center

Billings, MT

Temporarily Suspended

Bozeman Deaconess Hospital

Bozeman, MT

Open and Accepting

Benefis Sletten Cancer Institute

Great Falls, MT

Open and Accepting

Great Falls Clinic Specialty Center

Great Falls, MT

Temporarily Suspended

Kalispell Regional Medical Center

Kalispell, MT

Open and Accepting

Providence St. Patrick Hospital

Missoula, MT

Temporarily Suspended

Community Medical Hospital

Missoula, MT

Open and Accepting

Nebraska

Nebraska Cancer Specialists (Grand Island)

Grand Island, NE

Temporarily Suspended

Cancer Partners of Nebraska

Lincoln, NE

Temporarily Suspended

Nevada

OptumCare Cancer Care at Seven Hills

Henderson, NV

Open and Accepting

Optum Care Cancer Center - Charleston

Las Vegas, NV

Open and Accepting

OptumCare Cancer Care at Fort Apache

Las Vegas, NV

Open and Accepting

New Hampshire

Dartmouth-Hitchcock Medical Center Norris Cotton Cancer Center

Lebanon, NH

Open and Accepting

New Jersey

Memorial Sloan Kettering Basking Ridge

Basking Ridge, NJ

Open and Accepting

MD Anderson Cancer Center at Cooper Cooper University Hospital

Camden, NJ

Open and Accepting

Monmouth Medical Center Rutgers University

Long Branch, NJ

Open and Accepting

Memorial Sloan Kettering Monmouth

Middletown, NJ

Open and Accepting

Memorial Sloan Kettering Bergen

Montvale, NJ

Open and Accepting

Rutgers Cancer Institute of New Jersey Rutgers, The State University of New Jersey

New Brunswick, NJ

Open and Accepting

New Mexico

University of New Mexico Comprehensive Cancer Center

Albuquerque, NM

Open and Accepting

Memorial Medical Center - New Mexico Cancer Research Alliance (NMCRA)

Las Cruces, NM

Open and Accepting

New York

Memorial Sloan Kettering Cancer Center

New York, NY

Open and Accepting

Memorial Sloan Kettering Commack

Commack, NY

Open and Accepting

Hematology-Oncology Associates of Central New York, PC

East Syracuse, NY

Open and Accepting

C.R. Wood Cancer Center Glen Falls Hospital

Glens Falls, NY

Open and Accepting

University of Rochester Medical Center Wilmot Cancer Center Strong Memorial Hospital

Rochester, NY

Open and Accepting

SUNY Upstate Medical University State University of New York

Syracuse, NY

Open and Accepting

Memorial Sloan Kettering Nassau

Uniondale, NY

Open and Accepting

Upstate Cancer Center (Verona)

Verona, NY

Open and Accepting

Memorial Sloan Kettering Westchester

West Harrison, NY

Open and Accepting

North Carolina

UNC Lineberger Comprehensive Cancer Center University of North Carolina

Chapel Hill, NC

Open and Accepting

Southeastern Medical Oncology Center (Clinton)

Clinton, NC

Open and Accepting

Duke Cancer Center Duke University Medical Center

Durham, NC

Open and Accepting

Southeastern Medical Oncology Center (Goldsboro)

Goldsboro, NC

Open and Accepting

UNC Hospitals Hillsborough

Hillsborough, NC

Open and Accepting

Southeastern Medical Oncology Center (Jacksonville)

Jacksonville, NC

Open and Accepting

Vidant Oncology (Kenansville)

Kenansville, NC

Temporarily Suspended

Vidant Oncology - Kinston

Kinston, NC

Open and Accepting

Vidant Oncology (Richlands)

Richlands, NC

Temporarily Suspended

Ohio

Strecker Cancer Center (Belpre)

Belpre, OH

Open and Accepting

Adena Regional Medical Center

Chillicothe, OH

Temporarily Suspended

Cleveland Clinic (Fairview Hospital)

Cleveland, OH

Open and Accepting

Cleveland Clinic - Taussig Cancer Center Taussig Cancer Institute

Cleveland, OH

Open and Accepting

Ohio State University Comprehensive Cancer Center James Cancer Hospital and Solove Research Institute

Columbus, OH

Open and Accepting

Columbus Oncology and Hematology Associates

Columbus, OH

Temporarily Suspended

OhioHealth Riverside Methodist Hospital

Columbus, OH

Temporarily Suspended

OhioHealth Grant Medical Center

Columbus, OH

Temporarily Suspended

The Mark H. Zangmeister Center

Columbus, OH

Open and Accepting

Mount Carmel Health Center West

Columbus, OH

Temporarily Suspended

Doctors Hospital

Columbus, OH

Temporarily Suspended

Miami Valley Hospital

Dayton, OH

Temporarily Suspended

OhioHealth Grady Memorial Hospital Cancer Center

Delaware, OH

Temporarily Suspended

Dublin Methodist Hospital

Dublin, OH

Temporarily Suspended

Central Ohio Breast and Endocrine Surgery

Gahanna, OH

Temporarily Suspended

Mount Carmel Grove City Hospital

Grove City, OH

Temporarily Suspended

Fairfield Medical Center

Lancaster, OH

Temporarily Suspended

Saint Rita's Medical Center

Lima, OH

Temporarily Suspended

OhioHealth Mansfield Hospital

Mansfield, OH

Temporarily Suspended

Marietta Memorial Hospital

Marietta, OH

Open and Accepting

OhioHealth Marion General Hospital

Marion, OH

Temporarily Suspended

Memorial Hospital

Marysville, OH

Open and Accepting

Cleveland Clinic (Hillcrest Hospital)

Mayfield Heights, OH

Open and Accepting

Premier Health Atrium Medical Center - Middletown

Middletown, OH

Temporarily Suspended

Knox Community Hospital

Mount Vernon, OH

Temporarily Suspended

Licking Memorial Hospital

Newark, OH

Open and Accepting

Newark Radiation Oncology

Newark, OH

Temporarily Suspended

Mercy Health Perrysburg Cancer Center

Perrysburg, OH

Temporarily Suspended

Southern Ohio Medical Center

Portsmouth, OH

Open and Accepting

Springfield Regional Medical Center

Springfield, OH

Temporarily Suspended

Mercy Health - St. Anne Hospital

Toledo, OH

Temporarily Suspended

Toledo Clinic Cancer Centers - Toledo

Toledo, OH

Temporarily Suspended

Saint Vincent Mercy Medical Center

Toledo, OH

Temporarily Suspended

Premier Health Upper Valley Medical Center

Troy, OH

Temporarily Suspended

Saint Ann's Hospital

Westerville, OH

Temporarily Suspended

Mount Carmel Health Center (East)

Whitehall, OH

Temporarily Suspended

Wright-Patterson Medical Center

Wright-Patterson AFB, OH

Temporarily Suspended

Genesis HealthCare System

Zanesville, OH

Open and Accepting

Oklahoma

University of Oklahoma Health Sciences Center

Oklahoma City, OK

Open and Accepting

Mercy Hospital Oklahoma City

Oklahoma City, OK

Temporarily Suspended

Oregon

Saint Alphonsus Medical Center (Baker City)

Baker City, OR

Temporarily Suspended

St. Charles (Bend Campus)

Bend, OR

Open and Accepting

Clackamas Radiation Oncology Center

Clackamas, OR

Open and Accepting

Providence Cancer Institute Clackamas Clinic

Clackamas, OR

Temporarily Suspended

Bay Area Hospital

Coos Bay, OR

Temporarily Suspended

Providence Newberg Medical Center

Newberg, OR

Open and Accepting

Saint Alphonsus Medical Center (Ontario)

Ontario, OR

Open and Accepting

Providence Willamette Falls Medical Center

Oregon City, OR

Open and Accepting

Providence Oncology and Hematology - Eastside Providence Cancer Institute Franz Clinic

Portland, OR

Open and Accepting

Providence Oncology and Hematology - Westside Providence St. Vincent Medical Center

Portland, OR

Open and Accepting

Saint Charles Health System (Redmond)

Redmond, OR

Temporarily Suspended

Pennsylvania

Lehigh Valley Hospital-Cedar Crest

Allentown, PA

Open and Accepting

Lehigh Valley Hospital - Muhlenberg

Bethlehem, PA

Open and Accepting

Christiana Care Health System-Concord Health Center

Chadds Ford, PA

Temporarily Suspended

Geisinger Medical Center - Danville

Danville, PA

Open and Accepting

Pocono Medical Center

East Stroudsburg, PA

Temporarily Suspended

Lehigh Valley Hospital - Hazleton

Hazleton, PA

Temporarily Suspended

Thomas Jefferson University Hospital

Philadelphia, PA

Open and Accepting

Geisinger Wyoming Valley Medical Center Henry Cancer Center

Wilkes-Barre, PA

Open and Accepting

South Carolina

Prisma Health Cancer Institute - Spartanburg

Boiling Springs, SC

Open and Accepting

Medical University of South Carolina

Charleston, SC

Open and Accepting

Ralph H Johnson VA Medical Center VA Charleston

Charleston, SC

Open and Accepting

Prisma Health Cancer Institute - Easley Easley

Easley, SC

Open and Accepting

Greenville Health System Cancer Institute (Butternut)

Greenville, SC

Open and Accepting

Prisma Health Cancer Institute - Eastside Eastside

Greenville, SC

Open and Accepting

Prisma Health Cancer Institute - Faris

Greenville, SC

Open and Accepting

Prisma Health Cancer Institute - Greer Greer

Greer, SC

Open and Accepting

Prisma Health Cancer Institute - Seneca Lila Doyle Drive

Seneca, SC

Open and Accepting

Tennessee

Baptist Clinical Research Institute

Memphis, TN

Open and Accepting

Vanderbilt-Ingram Cancer Center Henry-Joyce Cancer Clinic

Nashville, TN

Open and Accepting

Texas

UT Southwestern Clinical Center at Richardson/Plano

Richardson, TX

Temporarily Suspended

Utah

Huntsman Cancer Institute University of Utah

Salt Lake City, UT

Open and Accepting

Virginia

Massey Cancer Center Virginia Commonwealth University (VCU Health)

Richmond, VA

Open and Accepting

Washington

Providence Regional Cancer System (Aberdeen)

Aberdeen, WA

Temporarily Suspended

PeaceHealth Medical Group

Bellingham, WA

Temporarily Suspended

St. Michael - Harrison Medical Center

Bremerton, WA

Open and Accepting

Providence Regional Cancer System (Centralia)

Centralia, WA

Temporarily Suspended

Swedish Cancer Institute Swedish Edmonds Campus

Edmonds, WA

Open and Accepting

Providence Everett Medical Center

Everett, WA

Temporarily Suspended

Swedish Cancer Institute

Issaquah, WA

Open and Accepting

Kadlec Clinic Hematology and Oncology

Kennewick, WA

Open and Accepting

Providence Regional Cancer System (Lacey)

Lacey, WA

Temporarily Suspended

Saint John Medical Center

Longview, WA

Temporarily Suspended

Jefferson Healthcare

Port Townsend, WA

Open and Accepting

Swedish Medical Center (Ballard Campus)

Seattle, WA

Temporarily Suspended

Fred Hutchinson Cancer Research Center University of Washington Cancer Consortium / SCCA

Seattle, WA

Open and Accepting

Swedish Cancer Institute - Cherry Hill Campus

Seattle, WA

Temporarily Suspended

Swedish - First Hill Campus

Seattle, WA

Open and Accepting

Seattle Cancer Care Alliance at UW Medical Center - Northwest

Seattle, WA

Open and Accepting

PeaceHealth United General Medical Center

Sedro-Woolley, WA

Temporarily Suspended

Providence Regional Cancer System (Shelton)

Shelton, WA

Temporarily Suspended

Northwest Medical Specialties (Tacoma) NWMS Tacoma — Medical Oncology & Infectious Diseases

Tacoma, WA

Temporarily Suspended

PeaceHealth Southwest Medical Center

Vancouver, WA

Open and Accepting

Providence St. Mary Regional Cancer Center

Walla Walla, WA

Temporarily Suspended

North Star Lodge Cancer Center

Yakima, WA

Open and Accepting

Providence Regional Cancer System (Yelm)

Yelm, WA

Temporarily Suspended

Washington, D.C.

Sibley Memorial Hospital The Johns Hopkins Hospital

Washington, DC

Open and Accepting

Wisconsin

University of Wisconsin - Carbone Cancer Center University of Wisconsin Health

Madison, WI

Open and Accepting

Langlade Hospital and Cancer Center

Antigo, WI

Temporarily Suspended

ThedaCare Regional Cancer Center

Appleton, WI

Open and Accepting

Essentia Health - Ashland Clinic

Ashland, WI

Open and Accepting

Marshfield Medical Center Cancer Center - Eau Claire

Eau Claire, WI

Open and Accepting

Bellin Memorial Hospital

Green Bay, WI

Open and Accepting

Marshfield Medical Center - Hospital

Marshfield, WI

Open and Accepting

Aspirus Medford Hospital

Medford, WI

Temporarily Suspended

Marshfield Clinic (Minocqua Center)

Minocqua, WI

Open and Accepting

Cancer Center of Western Wisconsin

New Richmond, WI

Open and Accepting

Aspirus Cancer Care - James Beck Cancer Center

Rhinelander, WI

Temporarily Suspended

Marshfield Clinic (Rice Lake Center)

Rice Lake, WI

Open and Accepting

Marshfield Clinic Cancer Care (Saint Michael's Hospital)

Stevens Point, WI

Open and Accepting

Aspirus Regional Cancer Center

Wausau, WI

Temporarily Suspended

Marshfield Medical Center St. Clare's Hospital

Weston, WI

Open and Accepting

Aspirus Cancer Care Aspirus Riverview Hospital

Wisconsin Rapids, WI

Temporarily Suspended

Wyoming

Cheyenne Regional Medical Center (West)

Cheyenne, WY

Temporarily Suspended

Billings Clinic (Cody)

Cody, WY

Temporarily Suspended

Welch Cancer Center

Sheridan, WY

Temporarily Suspended
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