Ibrutinib

Overview

Ibrutinib is a Bruton's tyrosine kinase (BTK) inhibitor that binds to and irreversibly inhibits BTK activity, thereby preventing both B-cell activation and B-cell-mediated signaling, which may result to decreased growth of cancer cells.

SparkCures ID 31
Developed By Pharmacyclics
Generic Name Ibrutinib
Additional Names Imbruvica, PCI-32765
Treatment Classifications

Clinical Trials

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Multiple Myeloma
Smoldering Myeloma
Monoclonal Gammopathy of Undetermined Significance (MGUS)

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