Carfilzomib

KYPROLIS®

Overview

Carfilzomib is a kind of medication called a proteasome inhibitor that interferes with the growth and spread of cancer cells in the body. Carfilzomib is used in the treatment of multiple myeloma. 

SparkCures ID 2
Developed By Amgen
Brand Name Kyprolis®
Generic Name Carfilzomib
Additional Names PR-171
Treatment Classifications

Clinical Trials

All Clinical Trials

View all active clinical trials around the US.

Verified
Phase 3 Clinical Trial Comparing the Safety and Efficacy of BMS-986393 to Standard of Care Regimens in Patients with Relapsed/Refractory Multiple Myeloma
QUINTESSENTIAL-2
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Verified
Phase 3 Clinical Trial Comparing the Safety and Effectiveness of Elranatamab Versus Commonly Used Combination Regimens in Participants with Relapsed/Refracto...
MAGNETISMM-32
View Trial
Verified
Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM
DARATUMUMAB COMBINATION THERAPY
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Verified
A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or Maplirpacept) in People With Relapsed Refractory Multiple Myeloma
MAGNETISMM-20
View Trial

SparkCures Verified Accurate, up-to-date information. Learn more

Phase 1B / 2 Study of Selinexor in Combination With Other Treatments for Relapsed/Refractory and Newly Diag...
STOMP
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A Phase 3, Randomized, Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Ver...
IMMAGINE-3
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A Phase 3, Multicenter, Randomized, Open Label Study of Etentamig Compared With Standard Available Therapie...
CERVINO
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A Study of Selinexor, in Combination With Carfilzomib, Daratumumab or Pomalidomide in Patients With Multipl...
SELINEXOR
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Phase II Clinical Trial of Mezigdomide/Carfilzomib/Dexamethasone (MeziKD) in Patients With Relapsed or Refr...
MEZIGDOMIDE, CARFILZOMIB, AND DEXAMETHASONE
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A Single-arm, Open-label, Phase 2 Study Evaluating Subcutaneous Administration of Isatuximab, Administered ...
SUBQSA
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Combination Treatment Therapy Approaches for the Treatment of High-Risk Multiple Myeloma, REACH Trial
REACH
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Phase II Study of Belantamab Mafodotin in Combination With Carfilzomib, Pomalidomide, and Dexamethasone (KP...
BELANTAMAB MAFODOTIN
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A Phase 1/2, Open-Label, Platform Study to Evaluate Safety and Efficacy of Etentamig Monotherapy or Etentam...
ETENTAMIG (ABBV-383)
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Phase 1 Trial of SX-682, a CXCR 1/2 Inhibitor, in Combination With Standard of Care Treatment in Patients W...
SX-682
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A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
MMSET INHIBITOR
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COMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomide (COMMANDER)
COMMANDER
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A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone...
SONROTOCLAX (BGB-11417)
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Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple Myeloma
IBERDOMIDE COMBINATION THERAPY (KID)
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A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments f...
LINVOSELTAMAB
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Study of Carfilzomib, Lenalidomide, Dexamethasone and Belantamab Mafodotin in Multiple Myeloma
BELANTAMAB MAFODOTIN
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Carfilzomib Based Chemotherapy Mobilization for Autologous Stem Cell Transplants in Multiple Myeloma (CarMob)
CARMOB
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Phase I Trial of GB1211 (Selvigaltin), an Oral Galectin-3 (Gal-3) Inhibitor, Combined With Standard of Care...
GB1211 (SELVIGALTIN) COMBINATION THERAPY
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Untreated / Newly Diagnosed Multiple Myeloma

The following is a listing of clinical trials for patients with multiple myeloma who have been newly diagnosed or have not yet received treatment.

Combination Treatment Therapy Approaches for the Treatment of High-Risk Multiple Myeloma, REACH Trial
REACH
View Trial
A Phase 1/2, Open-Label, Platform Study to Evaluate Safety and Efficacy of Etentamig Monotherapy or Etentam...
ETENTAMIG (ABBV-383)
View Trial
Study of Carfilzomib, Lenalidomide, Dexamethasone and Belantamab Mafodotin in Multiple Myeloma
BELANTAMAB MAFODOTIN
View Trial
Carfilzomib Based Chemotherapy Mobilization for Autologous Stem Cell Transplants in Multiple Myeloma (CarMob)
CARMOB
View Trial
Early Relapse Multiple Myeloma

The following is a listing of clinical trials for patients with multiple myeloma who have received one to two prior lines of therapy.

Verified
Phase 3 Clinical Trial Comparing the Safety and Efficacy of BMS-986393 to Standard of Care Regimens in Patients with Relapsed/Refractory Multiple Myeloma
QUINTESSENTIAL-2
View Trial
Verified
Phase 3 Clinical Trial Comparing the Safety and Effectiveness of Elranatamab Versus Commonly Used Combination Regimens in Participants with Relapsed/Refracto...
MAGNETISMM-32
View Trial
Verified
Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM
DARATUMUMAB COMBINATION THERAPY
View Trial
Verified
A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or Maplirpacept) in People With Relapsed Refractory Multiple Myeloma
MAGNETISMM-20
View Trial

SparkCures Verified Accurate, up-to-date information. Learn more

Phase 1B / 2 Study of Selinexor in Combination With Other Treatments for Relapsed/Refractory and Newly Diag...
STOMP
View Trial
A Phase 3, Randomized, Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Ver...
IMMAGINE-3
View Trial
A Phase 3, Multicenter, Randomized, Open Label Study of Etentamig Compared With Standard Available Therapie...
CERVINO
View Trial
A Study of Selinexor, in Combination With Carfilzomib, Daratumumab or Pomalidomide in Patients With Multipl...
SELINEXOR
View Trial
Phase II Clinical Trial of Mezigdomide/Carfilzomib/Dexamethasone (MeziKD) in Patients With Relapsed or Refr...
MEZIGDOMIDE, CARFILZOMIB, AND DEXAMETHASONE
View Trial
A Single-arm, Open-label, Phase 2 Study Evaluating Subcutaneous Administration of Isatuximab, Administered ...
SUBQSA
View Trial
Phase II Study of Belantamab Mafodotin in Combination With Carfilzomib, Pomalidomide, and Dexamethasone (KP...
BELANTAMAB MAFODOTIN
View Trial
Phase 1 Trial of SX-682, a CXCR 1/2 Inhibitor, in Combination With Standard of Care Treatment in Patients W...
SX-682
View Trial
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone...
SONROTOCLAX (BGB-11417)
View Trial
A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments f...
LINVOSELTAMAB
View Trial
Study of Carfilzomib, Lenalidomide, Dexamethasone and Belantamab Mafodotin in Multiple Myeloma
BELANTAMAB MAFODOTIN
View Trial
Carfilzomib Based Chemotherapy Mobilization for Autologous Stem Cell Transplants in Multiple Myeloma (CarMob)
CARMOB
View Trial
Phase I Trial of GB1211 (Selvigaltin), an Oral Galectin-3 (Gal-3) Inhibitor, Combined With Standard of Care...
GB1211 (SELVIGALTIN) COMBINATION THERAPY
View Trial
Late Relapse Multiple Myeloma

The following is a listing of clinical trials for patients with multiple myeloma who have received three or more prior lines of therapy.

Verified
Phase 3 Clinical Trial Comparing the Safety and Efficacy of BMS-986393 to Standard of Care Regimens in Patients with Relapsed/Refractory Multiple Myeloma
QUINTESSENTIAL-2
View Trial
Verified
Phase 3 Clinical Trial Comparing the Safety and Effectiveness of Elranatamab Versus Commonly Used Combination Regimens in Participants with Relapsed/Refracto...
MAGNETISMM-32
View Trial
Verified
Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM
DARATUMUMAB COMBINATION THERAPY
View Trial
Verified
A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or Maplirpacept) in People With Relapsed Refractory Multiple Myeloma
MAGNETISMM-20
View Trial

SparkCures Verified Accurate, up-to-date information. Learn more

Phase 1B / 2 Study of Selinexor in Combination With Other Treatments for Relapsed/Refractory and Newly Diag...
STOMP
View Trial
A Phase 3, Randomized, Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Ver...
IMMAGINE-3
View Trial
A Phase 3, Multicenter, Randomized, Open Label Study of Etentamig Compared With Standard Available Therapie...
CERVINO
View Trial
A Study of Selinexor, in Combination With Carfilzomib, Daratumumab or Pomalidomide in Patients With Multipl...
SELINEXOR
View Trial
Phase II Clinical Trial of Mezigdomide/Carfilzomib/Dexamethasone (MeziKD) in Patients With Relapsed or Refr...
MEZIGDOMIDE, CARFILZOMIB, AND DEXAMETHASONE
View Trial
A Single-arm, Open-label, Phase 2 Study Evaluating Subcutaneous Administration of Isatuximab, Administered ...
SUBQSA
View Trial
Phase II Study of Belantamab Mafodotin in Combination With Carfilzomib, Pomalidomide, and Dexamethasone (KP...
BELANTAMAB MAFODOTIN
View Trial
Phase 1 Trial of SX-682, a CXCR 1/2 Inhibitor, in Combination With Standard of Care Treatment in Patients W...
SX-682
View Trial
A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
MMSET INHIBITOR
View Trial
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone...
SONROTOCLAX (BGB-11417)
View Trial
A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments f...
LINVOSELTAMAB
View Trial
Study of Carfilzomib, Lenalidomide, Dexamethasone and Belantamab Mafodotin in Multiple Myeloma
BELANTAMAB MAFODOTIN
View Trial
Phase I Trial of GB1211 (Selvigaltin), an Oral Galectin-3 (Gal-3) Inhibitor, Combined With Standard of Care...
GB1211 (SELVIGALTIN) COMBINATION THERAPY
View Trial
Smoldering Myeloma
Monoclonal Gammopathy of Undetermined Significance (MGUS)

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